Although it is hard to be certain the sign on the building at the left of the picture appears to suggest that the building is the Grand Junction Hotel which was closed in 1968 and demolished in 1971. If this is correct then this will be the area…
Clearly visible is the Dean Clough Mill (where the words Crossley Kosset are visible). The bus appears to be a 681, a service to Bradford that still runs today (2017).